2,3,5,6-TETRAFLUOROBENZENEBORONIC ACID

2,3,5,6-TETRAFLUOROBENZENEBORONIC ACID - Names and Identifiers

Name	2,3,5,6-Tetrafluorobenzeneboronic acid
Synonyms	2,3,5,6-Tetrafluorophenylboronicacid 2,3,5,6-TETRAFLUOROPHENYLBORONIC ACID 2,3,5,6-Tetrafluorobenzeneboronic acid 2,3,5,6-TETRAFLUOROBENZENEBORONIC ACID (2,3,5,6-Tetrafluorophenyl)boronic acid (2,3,5,6-Tetrafluorophenyl)boronic acidB B-(2,3,5,6-Tetrafluorophenyl)boronic acid boronic acid, B-(2,3,5,6-tetrafluorophenyl)- Boronic acid, B-(2,3,5,6-tetrafluorophenyl)- BORONIC ACID,(2,3,5,6-TETRAFLUOROPHENYL)- (9CI)
CAS	511295-01-5
EINECS	640-450-0
InChI	InChI=1/C6H3BF4O2/c8-2-1-3(9)6(11)4(5(2)10)7(12)13/h1,12-13H

2,3,5,6-TETRAFLUOROBENZENEBORONIC ACID - Physico-chemical Properties

Molecular Formula	C6H3BF4O2
Molar Mass	193.89
Density	1.53
Melting Point	143-145°C
Boling Point	263℃
Flash Point	113℃
Vapor Presure	0.00525mmHg at 25°C
BRN	9200167
pKa	6.06±0.58(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.446

2,3,5,6-TETRAFLUOROBENZENEBORONIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
Hazard Note	Irritant

2,3,5,6-TETRAFLUOROBENZENEBORONIC ACID - Introduction

2,3,5, acid is an organic compound with the chemical formula C6H3BF4O2. The following is a description of its nature, use, preparation and safety information:

Nature:
- 2,3,5, acid is a colorless solid.
-It is soluble in polar solvents such as water, alcohols and ketones.
-Relatively stable in the air, but may decompose under the action of high temperature and strong oxidants.

Use:
- 2,3,5, acid is commonly used in Suzuki-Miyaura cross-coupling reactions in organic synthesis.
-As a derivative of aromatic phenol, it can be used as a precursor for ligands, fluorescent dyes and optical materials.
-In addition, it can also be used to synthesize other organic compounds and functional materials.

Preparation Method: The preparation of
- 2,3,5, acid is generally obtained by the borylation reaction of aromatic hydrocarbons. The specific preparation method can be:
1. Treat 2,3,5, acid ester with alcohol and hydrochloric acid to generate the corresponding boric acid.
2. Under alkaline conditions, boric acid is reacted with sodium borohydride to generate 2,3,5, acid.

Safety Information:
- 2,3,5, acid is a general organic compound, which is generally relatively safe under correct handling and storage.
-Due to the lack of detailed toxicity studies of this substance, safety measures should still be paid during use, such as wearing appropriate protective equipment (gloves, glasses, etc.).
-Waste should be disposed of in accordance with local chemical waste disposal regulations.

Last Update：2024-04-10 22:29:15